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Mouse Transforming Growth Factor-beta 3 (AF)

Mouse Transforming Growth Factor-beta 3 (AF)

Catalog Number:
P001418367ABE
Mfr. No.:
Abe32-12319
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      • Overview

        • Predicted MW: Dimer, 12.9/25.7 kDa (113/226 aa). Transforming growth factors (TGFs) are multifunctional peptides that regulate growth and differentiation in most cell types. The TGF-beta family of proteins signal through serine/threonine kinase receptors. TGF-beta isoforms (TGF-beta 1, -beta 2, and –beta 3) have overlapping, yet distinct biological actions in developing and adult tissues. TGF-beta 3 is an important factor in regulating cell adhesion and accelerating wound repair. TGF-beta 3 also functions during osteoblast proliferation, chemotaxis, and collagen synthesis.

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      • Properties
        • Protein Name
          Transforming growth factor beta-3, LAP
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          In solution: 10 mM acetic acid and 20% Ethanol at a concentration of 0.25 mg/mL
          Storage
          Store at 4°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
          Activity
          Biological Activity was determined by Inhibition of IL-4-induced HT-2 cell proliferationat = 1.0 x 10^6 units/mg

          More Information

          UniProt
          P10600
          Gene ID
          7043

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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