Name: Human Tumor Necrosis Factor-alpha
Price: Inquiry

- Overview
  - Predicted MW: Monomer, 17.5 kDa (158 aa). Tumor necrosis factor alpha (TNF-alpha) is an inflammatory cytokine secreted by macrophages, monocytes, neutrophils, T cells, and NK-cells following stimulation by bacterial lipopolysaccharide (LPS). TNF-alpha signal activation occurs through two receptors, TNFR1 and TNFR2. TNFR1 is expressed on most cell types, unlike TNFR2, which is expressed mainly on immune cells. TNF-alpha functions to stimulate phagocytosis in macrophages, chemoattract neutrophils, increase insulin resistance, and induce fever.
    
    Please contact us at for specific academic pricing.
- Properties
  - Protein Name
    
    Tumor necrosis facto, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, NTF
    
    Source
    
    Genetically modified E.coli
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Reducing and Non-Reducing SDS PAGE at >= 95%
    
    Formulation
    
    Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
    Sterile water at 0.1 mg/mL
    
    Storage
    
    Store at -20°C
    
    Endotoxin
    
    Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
    
    Activity
    
    Biological Activity was determined by Cytolysis of mouse L929 cells in the presence of Actinomycin D at
    
    More Information
    
    UniProt
    
    P01375
    
    Gene ID
    
    7124
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

Human Tumor Necrosis Factor-alpha

Human Tumor Necrosis Factor-alpha

More Information

We Also Recommend

Human Tumor Necrosis Factor-alpha (AF)

Mouse Tumor Necrosis Factor-alpha

Mouse Tumor Necrosis Factor-alpha (AF)