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Human Tumor Necrosis Factor Receptor Type 1

Human Tumor Necrosis Factor Receptor Type 1

Catalog Number:
P001418369ABE
Mfr. No.:
Abe32-12320
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      • Overview

        • Predicted MW: Monomer, 18.3 kDa (162 aa). Tumor necrosis factor receptor type 1 (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound tumor necrosis factor alpha (TNFa). TNFR1 activates NF-kB and MAPK pathways to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis, and inhibit viral replication.

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      • Properties
        • Protein Name
          Tumor necrosis factor receptor superfamily member 1A, Tumor necrosis factor receptor 1, Tumor necrosis factor receptor type I, p55, CD120a
          Source
          Genetically modified E.coli
          Type
          Recombinant Proteins
          Purification
          Reducing and Non-Reducing SDS PAGE at >= 95%
          Formulation
          Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
          Sterile water at 0.1 mg/mL
          Storage
          Store at -20°C
          Endotoxin
          Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
          Activity
          Biological Activity was determined by Neutralization of human TNF alpha induced L929 cell cytolysis at

          More Information

          UniProt
          P19438
          Gene ID
          7132

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

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