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Overview
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Mouse tPA Genetically Deficient Plasma is prepared from a tPA knockout mouse. This Tissue Plasminogen Activator (tPA) Knockout was created by targeted disruption of the PLAT gene. Mutations were then confirmed using PCR genotyping and Sanger sequencing. Processed with Na Citrate as the anticoagulant.
• Product Details
Species: Mouse
Antigen: tPA
Format: Frozen liquid
Storage Conditions: -70 C
• Mouse Model Details
Strain: C57BL6/SJL
Chromosome: 8
Gene: PLAT
Genomic Target: : Exon 4
Mutation: 16 base pair deletion
Phenotype: Complete absence of tPA expression as confirmed by Western Blot of brain tissue lysates, loss of tPA activity confirmed by ELISA.Please contact us at for specific academic pricing.
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Overview