Mevastatin (Compactin)

Mevastatin (Compactin)

Catalog Number:
MAR1341453TOK
Mfr. No.:
TOK-M004
Price:
$204
  • Size:
    10 mg
    Quantity:
    Add to Cart:
      • Overview
        • Mevastatin is a statin prodrug commonly used to combat hypercholesterolemia. Mevastatin is insoluble in water, and soluble in ethanol and DMSO at 25 mg/mL.

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          Background

          Mevastatin inhibits HMG-CoA reductase, a significant enzyme involved in the cholesterol synthesis pathway.

      • Properties
        • CAS Number
          73573-88-3
          Molecular Formula
          C23H34O5
          Molecular Weight
          390.51
          Appearance
          Crystals from aqueous ethanol; White powder
          Solubility
          DMSO: 20 mg/mL Ethanol: 25 mg/mL
          Other Properties
          Source: Penicillium Citrinum.
          Assay: ≥95.0%
          Loss on Drying: ≤2.0%
          Absorbance: UV max: 230, 237 and 246 nm (log ε 4.28, 4.30, 4.11)
          Melting Point: 152 °C
          Optical Rotation: [α]D22 = +283° (c = 0.48 in acetone)
          Purity Level: ≥90.0%
          Storage
          2-8 °C

          * For research use only

      • Applications
        • Application Description
          Cancer Applications: Research has shown that statin drugs including mevastatin have been able to inhibit melanoma cell growth when high concentrations are used.

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