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Overview
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Antimicrobial isolated from wasp venom.
Mastoparan X is one of the mastoparans that was first isolated from the venom of the Japanese yellow hornet. Mastoparan X shows considerable antimicrobial activity against Gram-positive bacteria and can stimulate phospholipase A2 activity as well as being a G protein activator that binds to Gi and Go. Mastoparan X exhibits potent anticancer activity toward human glioblastoma multiforme cells, a process that occurs by membranolytic activity leading to necrosis.
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