m-dPEG®₄-Thiol

m-dPEG®₄-Thiol

Catalog Number:
CR05357934QUA
Mfr. No.:
AQ-10792
Price:
$279
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      • Overview
        • m-dPEG®4-thiol, product number 10792, is a monodisperse PEGylation reagent designed to modify gold and silver surfaces or biomolecules that contain free, surface-accessible thiols. One end of the spacer terminates with a methyl group, while the other end terminates with a sulfhydryl. The sulfhydryl group forms dative bonds with gold and disulfides with free thiols under non-reducing conditions.

          This product is useful for the passivation of gold surfaces. The hydrophilic, non-immunogenic dPEG® spacer eliminates non-specific interactions with the gold surface.

          If reacted with free thiols on biomolecules, m-dPEG®4-thiol forms disulfide bonds. Moreover, the resulting conjugates display improved water solubility and increased hydrodynamic volume. Furthermore, conjugation of this product with biomolecules potentially reduces or eliminates non-specific interactions and immunogenicity.

          Please contact us at for specific academic pricing.

      • Properties
        • Categories
          Chemical Modification Reagents
          CAS Number
          52190-55-3
          Molecular Weight
          224.32; single compound
          Purity
          > 98%
          Other Properties
          dPEG® Spacer is 14 atoms and 15.8 Å

          * For Research Use Only

      • Reference
        • Greg T. Hermanson, Bioconjugate Techniques, 3rd Edition, Elsevier, Waltham, MA 02451, 2013, ISBN 978-0-12-382239-0; See Chapter 18, Discrete PEG Reagents, pp. 787-821, for a full overview of the dPEG® products.

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