Name: Linezolid
Price: 229.00 USD

- Overview
  - Linezolid is an oxazolidinone antibiotic and is effective against Gram-positive bacteria including certain strains of methicillin-resistant Staphylococcus aureus (MRSA).
    
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    Background
    
    Linezolid inhibits protein synthesis by binding to the 50S ribosomal subunit (23S rRNA) which prevents formation of the 70S initiation complex thus inhibiting mRNA translation. It is also a monoamine oxidase inhibitor displaying nonselective, reversible binding.
- Properties
  - CAS Number
    
    165800-03-3
    
    Molecular Formula
    
    C16H20FN3O4
    
    Molecular Weight
    
    337.35
    
    Appearance
    
    White or almost white powder
    
    Other Properties
    
    Source: Synthetic
    Assay: ≥ 98% (dried basis)
    Residue On Ignition: ≤0.1%
    Heavy Metals: ≤ 0.001%
    Loss on Drying: ≤1.0%
    Purity Level: ≥98.0%
    
    Storage
    
    Ambient; Protect from light
    
    * For research use only
- Applications
  - Application Description
    
    Spectrum: Effective for Gram-positive bacteria including certain strains of MRSA
    
    Eukaryotic Cell Culture Applications: Linezolid inhibits cytokine production from human peripheral blood monocytes in a dose-dependent manner. Linezolid was found to modify the acute phase inflammatory response. Linezolid inhibits cytokine production from human peripheral blood monocytes in a dose-dependent manner (Garcia-Roca et al, 2006).