Leukotriene B4 Receptor - ExpressMAX™ Human GPCR ORF Clones

Leukotriene B4 Receptor is a G protein-coupled seven transmembrane domain receptors. Its gene is located in very close proximity to another leukotriene receptor, BLT2, both in the Human and mouse genomes. The two receptors differ in their affinity and specificity for LTB4 being LTB4R a high-affinity receptor specific for LTB4 and in their pattern of expression. LTB4R is expressed primarily in leukocytes. Reduced disease severity in animal inflammatory models seen with LTB4 receptor antagonists and in mice with targeted deletion of BLT1 have revealed important roles for LTB4 and its receptors in regulating pathologic inflammation.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. -A)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

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