K4® Multiplier - Transfection Enhancer

- Overview
  - The knowledge that virtually all transfection methods are affected of the defenses of the innate immune system, led to the development of the K4® Multiplier.
    K4® Multiplier is based on advanced technology that effectively inhibits endosomal or cytosolic sensors, improving transfection efficiency and viability. In addition, it has been optimized and refined for easy use with existing otimized transfection protocols for a wide range of transfection applications.
    
    Highlights
    ·Compatible with virtually all transfection methods
    ·Simple application (additive to the cell culture medium)
    ·Reduces the detection of foreign DNA and RNA through the cell's sensors for nucleic acids
    ·Improves the transfection efficiency and vitality of cells
    
    Please contact us at for specific academic pricing.
- Properties
  - Categories
    
    Cell Line Transduction Reagent
    
    Other Properties
    
    Shelf Life: 1 year (from date of delivery)
    Assays: 1% additive to the medium. 3.5 ml are sufficient for 350 ml culture medium.
    
    Storage
    
    4℃ (do not freeze)
    
    Shipping
    
    At room temperature
    
    * Only for research purposes in vitro, not intended for human or animal diagnostic, therapeutic or other clinical uses.
- Applications
  - Application
    
    Cell Line Transduction
    
    Application Description
    
    Suitable for the transient and stable transfection of mammalian cell lines and also primary cells with DNA (plasmids, bacmids), RNA (mRNA, miRNA and siRNA) and modified nucleic acids (such as antisense oligonucleotides).
    Application areas:
    ·The production of proteins, antibodies and virus (e.g. AAV, adenovirus, lentivirus)
    ·Cotransfectionens of various nucleic acids, genome editing (e.g. CRISPR/Cas9, CRISPR/Cpf1) and gene silencing (gene knockdown)
- Reference
  - "Amyloid precursor protein causes fusion of promyelocytic leukemia nuclear bodies in human hippocampal areas with high plaque load." Marks et al., 2020, bioRxiv
    "Cisplatin protein binding partners and their relevance for platinum drug sensitivity." Möltgen et al., 2020, Cells, 9.6: 1322
    "Humulone modulation of GABAA receptors and its role in hops sleep-promoting activity." Benkherouf et al., 2020, Frontiers in neuroscience, 14: 1100

MSDS

Documents

Product Information and Protocol

Recommended applications, sorted by nucleic acid

K4® Multiplier - Transfection Enhancer

K4® Multiplier - Transfection Enhancer

Documents

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