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Overview
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Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6. Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography.
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Overview