Interleukin-6 human (IL-6) (RECOMBINANT)

Interleukin-6 human (IL-6) (RECOMBINANT)

Catalog Number:
P001277800AUS
Mfr. No.:
AUST_CI-460-33
Price:
$480
  • Size:
    25µg
    Quantity:
    Add to Cart:
      • Overview
        • Human Interleukin-6 (IL-6) plays a role in the mediation of the inflammatory and immune response initiated by infection or injury. IL-6 acts on B cells by stimulating differentiation and antibody secretion. IL-6 also exhibits growth factor activity for mature thymic or peripheral T cells, and enhances the differentiation of cytotoxic T cells in the presence of IL-2 or IFNt. This glycoprotein is composed of 184 amino acid residues, and has a 42% homology with murine IL-6. Human Interleukin-6 (RECOMBINANT) is produced in genetically engineered Spodoptera frugiperda insect cells (Sf9) infected with recombinant viruses, and purified by sequential chromatography.

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      • Properties
        • Type
          Recombinant Proteins
          Purification
          Over 85% pure by SDS gel electrophoresis. There is < 1ng/mg endotoxin.
          Formulation
          Frozen liquid solution (PBS) at 0.50 mg/ml (50 µl/vial)
          Storage
          Store at -80°C.
          Molecular Weight
          20-21 KDa (glycoprotein)
          Activity
          3H-thymidine uptake by B9 murine thymoma cell line that is IL-6 dependent.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Reference
        • 1. Taga, T., and Kishimoto, T., (1997) Ann. Rev. Immunology, 15, 797-819

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