IFN a 2a Recombinant Protein

IFN a 2a Recombinant Protein

Catalog Number:
P001412051ABE
Mfr. No.:
Abe32-1312
Price:
  • Size:
    100 µg
    Quantity:
    Add to Cart:
      • Overview
        • Interferon Alpha Human 2a Recombinant produced in E. Coli is a single, non-glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19241 Dalton. The Interferon-a 2a gene was obtained from human leukocytes. The IFN-A 2a is purified by proprietary chromatographic techniques. IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.

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      • Properties
        • Protein Name
          Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-a 2a.
          Source
          E. coli
          Type
          Recombinant Proteins
          Purification
          Greater than 97.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
          Formulation
          Lyophilized without additives.
          Storage
          Lyophilized Interferon alpha 2a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 2a should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to reconstitute the lyophilized Interferon-alpha 2a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The specific activity as determined in a viral resistance assay using bovine kidney MDBK cells was found to be 270,000,000 IU/mg.

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