Name: IFN a 2a Plant Recombinant Protein
Price: Inquiry

- Overview
  - Nicotiana Sp. Plant. Interferon Alpha Human 2a Recombinant produced in Plant is a single, glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of 19 kDa. The Interferon-a 2a contains affinity 6xHis tag on C-terminus. The IFN-A 2a is purified by proprietary chromatographic techniques. IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.
    
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- Properties
  - Protein Name
    
    Leukocyte interferon, B cell interferon, Type I interferon, IFNA2, IFN-a 2a.
    
    Type
    
    Recombinant Proteins
    
    Purification
    
    Greater than 99.0% as determined by both: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
    
    Formulation
    
    Lyophilized, containing 50% SDS.
    
    Storage
    
    Lyophilized Interferon alpha 2a although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 2a should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
    
    * For Research Use Only. Not for use in diagnostic/therapeutics procedures.
- Applications
  - Application Description
    
    It is recommended to reconstitute the lyophilized Interferon-alpha 2a in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The specific activity was determined by a quantitative gene report bioassay using human Type I interferon-sensitive cells. Compared with bacterial derived recombinant IFN-a 2a, assayed in the same conditions, plant derived IFN-alpha 2a showed 6.1 × 108 Units/mg in reference to a viral resistance assay using bovine kidney MDBK cells.

IFN a 2a Plant Recombinant Protein

IFN a 2a Plant Recombinant Protein

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