IFN a 2b Yeast Recombinant Protein

IFN a 2b Yeast Recombinant Protein

Catalog Number:
P001412054ABE
Mfr. No.:
Abe32-1315
Price:
  • Size:
    50 µg
    Quantity:
    Add to Cart:
      • Overview
        • Saccharomyces cerevisiae. Interferon-alpha 2b Human Recombinant produced in yeast is a single, glycosylated, polypeptide chain containing 165 amino acids and having a molecular mass of approximately 19 kDa. The Interferon-alpha 2b gene was obtained from human leukocytes. The IFN-a 2b is purified by proprietary chromatographic techniques. IFN-alpha is produced by macrophages and has antiviral activities. Interferon stimulates the production of two enzymes: protein kinase and an oligoadenylate synthetase.

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      • Properties
        • Protein Name
          Interferon alpha 2b, IFNA, INFA2, IFN-α 2b, MGC125764, MGC125765.
          Type
          Recombinant Proteins
          Purification
          Greater than 98.0% as determined by (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
          Formulation
          Lyophilized from a 0.2µm filtered concentrated (1mg/ml) solution in PBS, pH-7.4.
          Storage
          Lyophilized glycosilated IFN-a 2b although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-alpha 2b should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

          * For Research Use Only. Not for use in diagnostic/therapeutics procedures.

      • Applications
        • Application Description
          It is recommended to reconstitute the lyophilized glycosilated IFN alpha 2b in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The specific activity as determined in a viral resistance assay was found to be no less than 300,000,000IU/mg.

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