Hydroxy-dPEG®₂₄-TFP ester

Hydroxy-dPEG®24-TFP ester, product number 11349, is a hydroxy-terminated, single molecular weight, discrete polyethylene glycol (dPEG®) compound that has a 2,3,5,6-tetrafluorophenyl (TFP) ester for conjugation to primary and secondary amines. TFP esters outperform traditional N-hydroxysuccinimide (NHS) esters, because TFP esters are less susceptible to hydrolysis and more reactive towards primary and secondary amines than NHS esters. This product can be used for modification of amine-functionalized surfaces (e.g., silica, glass), modification of proteins and peptides at accessible amine sites on the molecules, and construction of dendrimers, among many other applications.

If you need a larger amount of our product that our normal package size please contact us and request a quote. Our commercial capabilities allow us to manufacture PN11345 in any size lot you need.

Application References:

Hermanson, G. T. Chapter 2, Functional Targets for Bioconjugation. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 127-228.
Hermanson, G. T. Chapter 3, The Reactions of Bioconjugation. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 229-258.
Hermanson, G. T. Chapter 8, Dendrimers and Dendrons. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 351-386.
Hermanson, G. T. Chapter 18, PEGylation and Synthetic Polymer Modification. Bioconjugate Techniques, 3rd edition. Academic Press: New York, 2013, 787-838.

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