Human transforming growth factor beta-1 (TGF beta-1) recombinant

Human transforming growth factor beta-1 (TGF beta-1) recombinant

Catalog Number:
P001277810AUS
Mfr. No.:
AUST_GF-230-2
Price:
$560
  • Size:
    5µg
    Quantity:
    Add to Cart:
      • Overview
        • Human Transforming Growth Factor beta1 (TGF- beta1 ) is stimulatory for cells of mesenchymal origin and inhibitory for cells of epithelial or neuroectodermal origin. Mature TGF- beta1 is a disulfide-linked homodimer of two chains composed of 112 amino acid residues each. There is a 70% homology between human TGF- beta1 and human TGF- beta2. Human TGF- beta1 is produced in genetically engineered bacteria, and purified by sequential chromatography.

          Please contact us at for specific academic pricing.

      • Properties
        • Type
          Recombinant Proteins
          Purification
          Over 98% pure by non-reduced SDS gel electrophoresis.
          Formulation
          25 µl (0.20 mg/ml) in 5 mM HCl (pH 2.5). Some of the liquid in the vial could have been evaporated with changes in the final volume. However, the 5µg of the protein are still inside the vial. We recommend, in order to control the proper concentration, to dilute the entire content to a known volume with 5mM HCl. Do not freeze this material.
          Storage
          Store at +4°C.
          Molecular Weight
          25 KDa (dimeric protein)
          Activity
          The biological activity of human TGF-&# beta1 is determined by measuring the acidification of the culture medium (Rat-1 cells) exposed to the growth factor.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Reference
        • 1. Ichijo, H. et al.(1994) The Journal of Biological Chemistry, Vol 266, No. 33, May, 22459-22464
          2. Yan, Z., Winawer, S., and Friedman, E., (1994) The Journal of Biological Chemistry, Vol 269, No. 18, May, 13231-13237.

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