Human STEAP1 full length protein-synthetic nanodisc

Human STEAP1 full length protein-synthetic nanodisc

Catalog Number:
P001561716DIM
Mfr. No.:
FLP100070
Price:
$1,013
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      • Overview

        • Target: STEAP1
          Tag: C-Flag Tag
          Synonyms: PRSS24; STEAP
          Protein Families: Transmembrane

          Please contact us at for specific academic pricing.

          Background

          STEAP1 is a cell-surface biomolecule composed by sixtransmembrane domains connected by intra- and extracellular loops. It is commonly found overexpressed in several types of cancers, namely in PCa, and is preferentially located at the tight or gap junctions. However, in nontumoural tissues and vital organs, STEAP1 protein presents low or absent expression, unveiling considerable specificity for cancer environment. Taking into account STEAP1 predicted transmembrane topology and cellular localization, it has been hypothesized that STEAP1 may play an important role as a transporter protein and can be involved in intercellular communication.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length STEAP1 protein has a MW of 39.9 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q9UHE8

          * For research use only.

    MSDS

    Documents

    Datasheet

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