Human SLC2A4 full length protein-synthetic nanodisc

Human SLC2A4 full length protein-synthetic nanodisc

Catalog Number:
P001561719DIM
Mfr. No.:
FLP100064
Price:
$1,013
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      • Overview

        • Target: SLC2A4
          Tag: C-Flag Tag
          Synonyms: GLUT4
          Protein Families: Druggable Genome, Transmembrane
          Protein Pathways: Adipocytokine signaling pathway, Insulin signaling pathway, Type II diabetes mellitus

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          Background

          This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008]

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length SLC2A4 protein has a MW of 54.6 kDa
          Expression system
          HEK293

          More Information

          UniProt
          P14672

          * For research use only.

    MSDS

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    Datasheet

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