Human recombinant MIP-1 beta

Human recombinant MIP-1 beta

Catalog Number:
P001277819AUS
Mfr. No.:
AUST_MI-300-3; AUST_MI-300-4
Price:
$450
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      • Overview
        • Macrophage Inflammatory Protein MIP-1 beta is part of the CC subfamily of the chemokine superfamily of chemoattractant cytokines. MIP-1 beta affects the inflammatory response of blood monocytes, tissue macrophages, and T cells. MIP-1 beta also enhances the formation of granulocyte-macrophage colonies stimulated by GM-CSF or M-CSF. Human MIP-1 beta is composed of 69 amino acid residues with one possible N-linked glycosylation sites, and several possible O-linked sites. Human MIP-1 beta is 60% homologous with human MIP-1 beta. Human recombinant MIP-1 beta is produced in genetically engineered yeast, and purified by sequential chromatography.

          Please contact us at for specific academic pricing.

      • Properties
        • Type
          Recombinant Proteins
          Purification
          Over 95% pure by SDS gel electrophoresis, with low level of endotoxin.
          Formulation
          In water at a concentration of 1.0 mg protein/ml
          Storage
          Store at -80°C.
          Molecular Weight
          8 KDa
          Activity
          The biological activity of recombinant human MIP-1 alpha is determined by its use as a cofactor for CSF-dependent myelopoiesis.

          * For research use ONLY in laboratory animals and in vitro testing. NOT for diagnostic or human use.

      • Reference
        • 1. Nathan, C.F. (1987)J. Clin. Invest. 79:319
          2. Tekamp-Olson. P. et al. (1990) J. Exp. Med. 172:911
          3. Wolpe S.D. et al. (1989) Proc. Natl. Acad. Sci. (USA) 86:612

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