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Human PVRIG full length protein-synthetic nanodisc

Human PVRIG full length protein-synthetic nanodisc

Catalog Number:

P001561730DIM

Mfr. No.:

FLP100041

Price:

$1,013

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- Overview
  - Target: PVRIG
    Tag: C-Flag Tag
    Synonyms: C7orf15; CD112R
    Protein Families: Transmembrane
    
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    Background
    
    Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
- Properties
  - Type
    
    Synthetic Nanodiscs
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
    
    Storage
    
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    
    Molecular Weight
    
    The human full length PVRIG protein has a MW of 34.3 kDa
    
    Expression system
    
    HEK293
    
    More Information
    
    UniProt
    
    Q6DKI7
    
    * For research use only.

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