Human LIPH (Lipase H) CLIA Kit

Lipase Member H; Liph; Lpd Lipase-Related Protein; Membrane-Associated Phosphatidic Acid-Selective Phospholipase A1-Alpha; Mpa-Pla1 Alpha; Phospholipase A1 Member B

LIPH_HUMAN ; Reactome: R-HSA-1483166 ; Gene ID: 200879

Tissue Specificity: Present in intestine (at protein level). Expressed in colon, prostate, kidney, pancreas, ovary, testis, intestine, lung and pancreas. Expressed at lower level in brain, spleen and heart. In hair, it is prominently expressed in hair follicles, including the stem cell-rich bulge region.

Function: Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA.a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).