Human HRH3 full length protein-synthetic nanodisc

Human HRH3 full length protein-synthetic nanodisc

Catalog Number:
P001561761DIM
Mfr. No.:
FLP100133
Price:
$1,013
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      • Overview

        • Target: HRH3
          Tag: C-Flag Tag
          Synonyms: GPCR97; HH3R
          Protein Families: Druggable Genome, Transmembrane
          Protein Pathways: Neuroactive ligand-receptor interaction

          Please contact us at for specific academic pricing.

          Background

          Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length HRH3 protein has a MW of 48.7 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q9Y5N1

          * For research use only.

    MSDS

    Documents

    Datasheet

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