Name: Human HRH3 full length protein-synthetic nanodisc
Price: 1013.00 USD

- Overview
  - Target: HRH3
    Tag: C-Flag Tag
    Synonyms: GPCR97; HH3R
    Protein Families: Druggable Genome, Transmembrane
    Protein Pathways: Neuroactive ligand-receptor interaction
    
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    Background
    
    Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system.
- Properties
  - Type
    
    Synthetic Nanodiscs
    
    Conjugate
    
    Unconjugated
    
    Formulation
    
    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
    
    Storage
    
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    
    Molecular Weight
    
    The human full length HRH3 protein has a MW of 48.7 kDa
    
    Expression system
    
    HEK293
    
    More Information
    
    UniProt
    
    Q9Y5N1
    
    * For research use only.

MSDS

Documents

Datasheet

Human HRH3 full length protein-synthetic nanodisc

Human HRH3 full length protein-synthetic nanodisc

Background

More Information

Documents

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