Human CFB (Complement Factor B) ELISA Kit

Complement Factor B; C3/C5 Convertase; Glycine-Rich Beta Glycoprotein; Gbg; Pbf2; Properdin Factor B Cleaved Into - Complement Factor B Ba Fragment - Complement Factor B Bb Fragment

Uniprot ID: MYH9_HUMAN ; Reactome: R-HSA-173736 ; Gene ID: 629

Function: Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. It has also been implicated in proliferation and differentiation of preactivated B-lymphocytes, rapid spreading of peripheral blood monocytes, stimulation of lymphocyte blastogenesis and lysis of erythrocytes. Ba inhibits the proliferation of preactivated B-lymphocytes.