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Overview
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Target Information
Target NameCholesteryl Ester Transfer Protein; Lipid Transfer Protein IDatabase LinksUniprot ID: MYH10_HUMAN ; Reactome: R-HSA-8964041 ; Gene ID: 1071About TargetTissue Specificity: Expressed by the liver and secreted in plasma.
Function: Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL. Regulates the reverse cholesterol transport, by which excess cholesterol is removed from peripheral tissues and returned to the liver for elimination.
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Overview