Human CD81 full length protein-synthetic nanodisc

Human CD81 full length protein-synthetic nanodisc

Catalog Number:
P001561724DIM
Mfr. No.:
FLP100050
Price:
$1,013
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      • Overview

        • Target: CD81
          Tag: C-Flag Tag
          Synonyms: CVID6; S5.7; TAPA1; TSPAN28
          Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
          Protein Pathways: B cell receptor signaling pathway

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          Background

          The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length CD81 protein has a MW of 25.6 kDa
          Expression system
          HEK293

          More Information

          UniProt
          P60033

          * For research use only.

    MSDS

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    Datasheet

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