Human CD47 full length protein-synthetic nanodisc

Human CD47 full length protein-synthetic nanodisc

Catalog Number:
P001561703DIM
Mfr. No.:
FLP100039
Price:
$1,013
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      • Overview

        • Target: CD47
          Tag: C-Flag Tag
          Synonyms: IAP; MER6; OA3
          Protein Families: Druggable Genome, Transmembrane
          Protein Pathways: ECM-receptor interaction

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          Background

          A membrane protein involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The encoded protein is also a receptor for the C-terminal cell binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This gene has broad tissue distribution, and is reduced in expression on Rh erythrocytes.

      • Properties
        • Type
          Synthetic Nanodiscs
          Conjugate
          Unconjugated
          Formulation
          Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
          Storage
          Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
          Molecular Weight
          The human full length CD47 protein has a MW of 35.2 kDa
          Expression system
          HEK293

          More Information

          UniProt
          Q08722

          * For research use only.

    MSDS

    Documents

    Datasheet

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