Name: Human CD4 [SP35] Monoclonal Antibody
Price: 200.00 USD

Overview
- Sensitivity: Endogenous
  Target name: Human CD4 [SP35] monoclonal antibody
  Area: Immunology/Cancer/Tumor Marker
  
  Please contact us at for specific academic pricing.
  
  Background
  
  This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
Properties
- Host
  
  Rabbit
  
  Antibody Type
  
  monoclonal
  
  Reactivity
  
  Human
  
  Clone
  
  mAb
  
  Storage
  
  Long time storage is recommended at -20°C
  Phosphate-buffered solution, pH 7.2, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
  Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
  
  * For research use only.