Collagen II / COL2A1 Antibody

Collagen II / COL2A1 Antibody

Catalog Number:
A001547464IRE
Mfr. No.:
IR296-1s; IR296-1
Price:
$180
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      • Overview
        • Sensitivity: Endogenous
          Target name: Collagen II /COL2A1
          Area: ECM Profiling / EMT

          Please contact us at for specific academic pricing.

          Background

          This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008]

      • Properties
        • Host
          Rabbit
          Antibody Type
          polyclonal
          Isotype
          IgG
          Reactivity
          Human, Mouse, Rat
          Clone
          pAb
          Storage
          Long time storage is recommended at -20°C
          Phosphate-buffered solution, pH 7.2, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative
          Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
          Molecular Weight
          180-200

          * For research use only.

      • Applications
        • Application
          WB; IF; IHC
        • Application Dilutions
          Western Blot 1:1000
          Immunofluorescence 1:300–1:500
          Immunohistochemistry (Paraffin) 1:100–1:200

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