Human Adiponectin ELISA Kit (ADP)

Adiponectin; 30 Kda Adipocyte Complement-Related Protein; Adipocyte Complement-Related 30 Kda Protein; Acrp30; Adipocyte - C1q And Collagen Domain-Containing Protein; Adipose Most Abundant Gene Transcript 1 Protein; Apm-1; Gelatin-Binding Protein

Uniprot ID: ANGL1_HUMAN ; Reactome: R-HSA-163680 ; Gene ID: 9370 ; Gene Symbol: ADIPOQ

Function: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.