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Overview
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This APOA5 ELISA kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in cell culture supernatant, serum and plasma (EDTA, citrate, heparin).
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Target Information
Target NameApolipoprotein A-V; Apo-Av; Apoa-V; Apolipoprotein A5; Regeneration-Associated Protein 3Database LinksUniprot ID: ASGR1_HUMAN ; Reactome: R-HSA-1989781 ; Gene ID: 116519 ; Gene Symbol: APOA5About TargetFunction: Minor apolipoprotein mainly associated with HDL and to a lesser extent with VLDL. May also be associated with chylomicrons. Important determinant of plasma triglyceride (TG) levels by both being a potent stimulator of apo-CII lipoprotein lipase (LPL) TG hydrolysis and an inhibitor of the hepatic VLDL-TG production rate (without affecting the VLDL-apoB production rate). Activates poorly lecithin:cholesterol acyltransferase (LCAT) and does not enhance efflux of cholesterol from macrophages. Binds heparin.
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