Human ADCY1 (Adenylate Cyclase 1, Brain) CLIA Kit

Adenylate Cyclase Type 1; Atp Pyrophosphate-Lyase 1; Adenylate Cyclase Type I; Adenylyl Cyclase 1; Ca(2+/Calmodulin-Activated Adenylyl Cyclase

Uniprot ID: DOPD_HUMAN ; Reactome: R-HSA-163359 ; Gene ID: 107

Tissue Specificity: Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level). Brain, retina and adrenal medulla.

Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. Mediates responses to increased cellular Ca(2+)/calmodulin levels. May be involved in regulatory processes in the central nervous system. May play a role in memory and learning. Plays a role in the regulation of the circadian rhythm of daytime contrast sensitivity probably by modulating the rhythmic synthesis of cyclic AMP in the retina.