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Overview
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This ADAM9 CLIA Kit is a highly sensitive in-vitro chemiluminescent immunoassay for the measurement of trace amounts of analytes.
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Target Information
Target NameDisintegrin And Metalloproteinase Domain-Containing Protein 9; Adam 9; Cellular Disintegrin-Related Protein; Meltrin-Gamma; Metalloprotease/Disintegrin/Cysteine-Rich Protein 9; Myeloma Cell MetalloproteinaseDatabase LinksUniprot ID: DBP_HUMAN ; Reactome: R-HSA-1442490 ; Gene ID: 8754About TargetTissue Specificity: Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart.
Function: Cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins. Isoform 2: May act as alpha-secretase for amyloid precursor protein (APP).
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