HTSphere™ 96-Well Plate for High-Throughput 3D Tissue Culture

The HTSphereTM 96-well Plate is designed for high-throughput spheroid culture, ECM embedding and drug testing. Each well contains a hydrogel insert that facilitates the formation of spheroids/organoid arrays with up to 12 uniform models per insert. The HTSphere platform makes 3D culture faster, more reproducible, and better suited to real-time and post-experimental analysis.

The HTSphere™ Platform is a transparent hydrogel insert that fits within each well of a 96-well plate. The HTSphere™ Platform allows making an array of 6 to 12 spheroid/organoids with a uniform size and can potentially combine ECM integration and drug testing followed by spheroid formation in the plate. The formed spheroids can be used for various downstream analyses either on a plate or after extracting the spheroids from the plate. The insert is perfectly suited to various assays and is compatible with standard laboratory imaging equipment, making it suitable to a wide range of experiments. ​​​

HTSphere Plate Specifications:
• Insert diameter: 6.5 mm (fits the wells of 96-well plates)
• Number of microwells per device: 6 or 12
• Microwell diameter at base: 500 μm
• Spheroid size range: 100 - 400 μm (depending on cell seeding density)

ADVANTAGES
• 96-well plate with an array of spheroids per well (up to 1152 per plate).
• One-step cell seeding.
• Monosize spheroids for experimental consistency.
• Compatible with automated cell dispensing systems.
• Effortless immunostaining and imaging.
• The platform can be directly embeddable in paraffin for IHC and H&E analysis.

Please contact us at for specific academic pricing.