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Overview
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Hexyl-4-pentynoic acid is a valproic acid analog. Histone deacetylase (HDAC) inhibitor, IC50=13 mM1. More potent and robust than valproic acid at inducing histone hyperacetylation (600% at 50 mM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons. Cell permeable.
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- Properties
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Overview