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Apicidin

Apicidin

Catalog Number:

I001528153REA

Mfr. No.:

EI-HDC-006

Price:

$280

Size:

1 mg

Quantity:

Add to Cart:

- Overview
  - Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinexcarbonyl]
    
    Apicidin is a cyclopeptide inhibitor of histone deacetylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1a protein levels and transcriptional activity in human and mouse tumor cell lines.Cell permeable.
    
    Please contact us at for specific academic pricing.
- Properties
  - Molecular Formula
    
    C34H49N5O6
    
    Molecular Weight
    
    MW=623.8
    
    Appearance
    
    white powder
    
    Solubility
    
    Solubilization: Soluble in DMSO (10 mg/ml); or ethanol (1 mg/ml)
    
    Storage
    
    Stable for at least 1 year after receipt when stored, as supplied, at -20°C. Stock solutions are stable for up to 3 months at -20°C.
    
    * For Research Use Only.
- Applications
  - Application
    
    Epigenetic Inhibitors

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