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Overview
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Cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinexcarbonyl]
Apicidin is a cyclopeptide inhibitor of histone deacetylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1a protein levels and transcriptional activity in human and mouse tumor cell lines.Cell permeable.Please contact us at for specific academic pricing.
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