Histamine Receptor H1 - ExpressMAX™ Human GPCR ORF Clones

Histamine Receptor H1 is a member of the Rhodopsin like GPCR family. It is activated by the biogenic amine histamine. HRH1 is expressed in smooth muscles, in the heart and in the Central Nervous System. It is linked to an intracellular G-protein (Gq) that activates phospholipase C and the phosphatidylinositol signaling pathway. Antihistamines are used as anti-allergic Drugs. The production of prostaglandin E2 synthase induces the histamine release from neurons, causing systemic vasodilation, contraction of smooth muscles and increased capillary permeability due to its action on HRH1.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

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