Histamine Receptor H2 - ExpressMAX™ Human GPCR ORF Clones

Histamine Receptor H2 is a member of the Rhodopsin like GPCR family. HRH2 is positively coupled to adenylate cyclase via Gs and is a potent stimulant of cAMP production, increases the intracellular Ca2+ levels and releases Ca2+ from intracellular stores. It is in the gastric parietal cells, vascular smooth muscle, neutrophils, Central Nervous System, heart and uterus. HRH2 stimulates gastric acid secretion, regulates gastrointestinal motility and intestinal secretion, smooth muscle relaxation and inhibit antibody production, T-cell proliferation and cytokine synthesis.

Includes:
ExpressMAX™ GPCR ORF Clones (Cat. No. – B)
– Vector as transformed Bacteria in stab culture or a Glycerol Stock format.
Mammalian Transfection Kits (Cat. No. – PLUS)
– 15 µg ExpressMAX™ Mammalian Expression Vector (1 mg/mL).
– 0. 2 mL CANFAST™ Transfection Reagent.

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