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Overview
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Hexokinase (EC 2.7.1.1, HK, ATP-dependent Hexokinase) plays an important role in glucose metabolism. Hexokinase deficiency leads to diseases such as X-linked muscular dystrophy and rare autosomal recessive hemolytic anemia. On the other hand, increased hexokinase activity is detected in various human tumors and is associated with metastasis.
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