[²H₈]-Abemaciclib Standards for LC-MS/MS

Name: [²H₈]-Abemaciclib Standards for LC-MS/MS
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SILS567276SHI

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SHI-C6976

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Overview

Abemaciclib is intended for Pharmaceuticals applications; it is a type of cancer growth blocker that targets the proteins cyclin dependant kinase 4 and 6 (CDK4 and CDK6) and a treatment for breast cancer. All information about [2H8]-Abemaciclib is provided in the MSDS. We deliver compounds with high purity levels and a comprehensive Certificate of Analysis.

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Properties

Alternative Name

Abemaciclib-D8, N-[5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine-D8, LY-2835219-D8

CAS Number

1231929-97-7 unlabeled

Molecular Formula

C27H24D8F2N8

Molecular Weight

514.66 g/mol

Purity

0.98

Solubility

refer to COA

Other Properties

Min. isotopic enrichment: 98%2 H
Stability: ≥ 1 year

* For research use only.

Reference

Therapeutic drug monitoring in breast cancer therapy – LC-MS/MS method for quantification of the CDK4/6 inhibitors abemaciclib, palbociclib, ribociclib, and major metabolites abemaciclib M20 and M2 in human serum. Journal of Pharmaceutical and Biomedical Analysis

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