Enterocin

- Overview
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    Background
    
    Enterocin is an antibiotic isolated from cultures of two strains of Streptomyces, Streptomyces candidus var. enterostaticus WS-8096 and variant M-127 of Streptomyces viridochromogenes. This antibiotic shows activity against Gram-positive and Gram-negative bacteria, especially against the Enterobacteriaceae [1]. Enterocin was named for its strong activity against Enterobacteriaceae.
    The elementary analysis and mass spectroscopic measurement suggested that the molecular formula was C72H20O10. The ultraviolet absorption gave two maximal peaks at 250 nm and 283 nm in methanol [1]. The mechanism of enterocin is unknown. Enterocin acts synergistically with streptomycin and chloramphenicol. The genetics of enterocin biosynthesis has been extensively investigated. Enterocin is a small molecular weight secondary metabolite [1].
    
    [1] Miyairi N, SAKAI H E I I, KONOMI T, et al. Enterocin, a new antibiotic [J]. The Journal of antibiotics, 1976, 29(3): 227-235.
- Properties
  - Categories
    
    antibiotic
    
    Alternative Name
    
    Vulgamycin; (3R,4aR,5S,6S,7S,7aS,8R)-7-benzoylhexahydro-4a,6,7a,8-tetrahydroxy-5-(4-methoxy-2-oxo-2H-pyran-6-yl)-3,6-methanocyclopenta[c]pyran-1(3H)-one
    
    CAS Number
    
    59678-46-5
    
    Molecular Formula
    
    C22H20O10
    
    Molecular Weight
    
    444.4
    
    Appearance
    
    A solid
    
    Purity
    
    Purity ≥95.00%
    
    Solubility
    
    Soluble in DMSO
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    O=C1[[email protected]@]2(O)[[email protected]@]([[email protected]@H](C(O3)=CC(OC)=CC3=O)[[email protected]]4(O)[[email protected]@H]2C(C5=CC=CC=C5)=O)(O)C[[email protected]@]([[email protected]]([H])4O)([H])O1
    
    * For Research Use Only

Documents

COA (Certificate Of Analysis)

MSDS (Material Safety Data Sheet)

Datasheet

Enterocin

Background

Documents

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