Dodecyl b-D-maltopyranoside

Dodecyl b-D-maltopyranoside

Catalog Number:
D001144770BIO
Mfr. No.:
DD06199
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      • Overview

        • Dodecyl maltoside (DDM) is a non-ionic detergent that consists of a hydrophilic maltose head and a hydrophobic long chain alkyl tail. It has a relatively low critical micelle concentration of 0.17 mM and is considered a gentle but powerful detergent. DDM is often the best tool for solubilising/crystallising membrane proteins. Membrane proteins usually have α-helical structures that are easily destroyed when the protein is released from its membrane environment. DDM can often preserve these structures during the solubilisation. In addition, membrane proteins can often be renatured when isolated with DDM.

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      • Properties
        • Alternative Name
          DDM;Lauryl maltoside;n-Dodecyl 4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside
          CAS Number
          69227-93-6
          Molecular Formula
          C24H46O11
          Molecular Weight
          510.62 g/mol
          MDL Number
          MFCD00043012
          Note
          There is no hazardous surcharge associated with this product.
          There is no special packaging charge associated with this product.

          * For research use only. Not for human or veterinary use

      • Reference

        • VanAken et al (1986) Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins. Methods in enzymology 125:27–35.
          Brown et al (1970) Synthesis and properties of some α-D-alkyl glucosides and mannosides: apparent molal volumes and solubilization of nitrobenzene in water at 25 °C. Canadian Journal of Chemistry 48(16): 2525-2531.

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