Dodecyl b-D-maltopyranoside - Amerigo Scientific

- Overview
  - Dodecyl maltoside (DDM) is a non-ionic detergent that consists of a hydrophilic maltose head and a hydrophobic long chain alkyl tail. It has a relatively low critical micelle concentration of 0.17 mM and is considered a gentle but powerful detergent. DDM is often the best tool for solubilising/crystallising membrane proteins. Membrane proteins usually have α-helical structures that are easily destroyed when the protein is released from its membrane environment. DDM can often preserve these structures during the solubilisation. In addition, membrane proteins can often be renatured when isolated with DDM.
    
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- Properties
  - Alternative Name
    
    DDM;Lauryl maltoside;n-Dodecyl 4-O-(a-D-glucopyranosyl)-b-D-glucopyranoside
    
    CAS Number
    
    69227-93-6
    
    Molecular Formula
    
    C24H46O11
    
    Molecular Weight
    
    510.62 g/mol
    
    MDL Number
    
    MFCD00043012
    
    Note
    
    There is no hazardous surcharge associated with this product.
    There is no special packaging charge associated with this product.
    
    * For research use only. Not for human or veterinary use
- Reference
  - VanAken et al (1986) Alkyl glycoside detergents: synthesis and applications to the study of membrane proteins. Methods in enzymology 125:27–35.
    Brown et al (1970) Synthesis and properties of some α-D-alkyl glucosides and mannosides: apparent molal volumes and solubilization of nitrobenzene in water at 25 °C. Canadian Journal of Chemistry 48(16): 2525-2531.