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Overview
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Diethyl Pyrocarbonate (DEPC) also known as diethyl dicarbonate is a chemical compound used to inactivate RNase and DNase enzymes via modification of Histidin residues in proteins to N-carbethoxy histidin and is sensitive to moisture and pH. DEPC at 155°C decomposes to ethanol and carbon dioxide in aqueous solution. Ammonia also decomposes DEPC to urethane, which is known as a potential carcinogen.
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Overview
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