Deguelin

- Overview
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    Background
    
    Anticancer and antiviral agent; chemopreventive and pro-apoptotic. Inhibits phorbol ester-induced ornithine decarboxylase and NADH:ubiquinone oxidoreductase activities (IC50 values are 11 and 6.9 nM respectively). Inhibits PI 3-kinase and reduces pAkt levels in pre-malignant and malignant human bronchial epithelial cells. Active in vivo.
- Properties
  - Categories
    
    Anticancer and antiviral agent
    
    CAS Number
    
    522-17-8
    
    Molecular Formula
    
    C23H22O6
    
    Molecular Weight
    
    394.42
    
    Appearance
    
    A crystalline solid
    
    Purity
    
    98.00%
    
    Solubility
    
    Soluble in DMSO
    
    Storage
    
    Store at 4°C
    
    SMILES
    
    [H][[email protected]]12[[email protected]](C(C(C=CC3=C4C=CC(C)(C)O3)=C4O2)=O)([H])C5=CC(OC)=C(OC)C=C5OC1
    
    * For Research Use Only