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Decitabine

Decitabine

Catalog Number:
I001528180REA
Mfr. No.:
EI-DNA-001
Price:
$333
  • Size:
    10 mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • 5-Aza-2'-deoxycytidine; 5-AzadCyD; NSC-127716

          Decitabine inhibits DNA methyltransferase. Induces demethylation and reactivation of silenced genes suppressing the growth of human tumor cell lines. Increases stem cell reprogramming efficiency. Stimulates osteogenic differentiation of human bone marrow stromal cells. Induces differentiation and growth inhibition in IDH1 mutant glioma cells and decreases tumor growth in vivo. An extremely useful reagent for inhibition of DNA methyltransferases in a variety of experimental systems including zebrafish embryos. Cell permeable. Active in vivo.

          Please contact us at for specific academic pricing.

      • Properties
        • Molecular Formula
          C8H12N4O4
          Molecular Weight
          MW=228.2
          Appearance
          White powder; MP=193-196°C
          Solubility
          Solubilization: May be dissolved in DMSO (25 mg/ml); or water (11 mg/ml).Ethanol (nil)
          Storage
          Store desiccated as supplied at 4°C for up to 2 years. Store solutions at-20°C for up to 3 months.

          * For Research Use Only.

      • Applications
        • Application
          Epigenetic Inhibitors

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