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5-Fluoro-2'-deoxycytidine

5-Fluoro-2'-deoxycytidine

Catalog Number:
I001528183REA
Mfr. No.:
EI-DNA-004
Price:
$288
  • Size:
    50 mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • 5-Fluoro-2'-deoxycytidine; FCDR; FdCyd; NSC-48006; Ro 5-1090

          2'-Deoxy-5-Fluorocytidine DNA methyltransferase inhibitor currently in clinical trials for breast cancer and other solid tumors. Like 5'-Azacytidineand decitabine, 2'-Deoxy-5-fluorocytidine is a pyrimidine analog that integrates into chromatin to inhibit DNA methylation. It blocks proliferation in colon cancer-derived HCT116 cells by activating DNA response pathways. It inhibits various strains of pathogenic avian influenza viruses in vitro and in vivo.

          Please contact us at for specific academic pricing.

      • Properties
        • Molecular Formula
          C9H12FN3O4
          Molecular Weight
          MW=245.2
          Appearance
          White solid; MP = 196oC
          Solubility
          Solubilization: May be dissolved in DMSO (20 mg/ml)
          Storage
          Store desiccated as supplied at -20°C for up to 2 years. Store solutions at-20°C for up to 1 month.

          * For Research Use Only.

      • Applications
        • Application
          Epigenetic Inhibitors

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