Name: CyFlow™ CD62L Low Endotoxin
Price: 324.00 USD

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).
- Properties
  - Host
    
    rat
    
    Antibody Type
    
    monoclonal
    
    Isotype
    
    IgG2a
    
    Reactivity
    
    mouse
    
    Clone
    
    MEL-14
    
    Immunogen
    
    C3H/eb mouse B cell lymphoma 38C-13
    
    Conjugate
    
    Low Endotoxin
    
    Formulation
    
    The reagent is provided in azide-free phosphate buffered saline (PBS) solution, pH ≈7.4; 0.2 µm filter sterilized. Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.
    
    Storage
    
    Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
    
    Concentration
    
    1 mg/mL
    
    Regulatory Status
    
    RUO
    
    Antigen
    
    L-selectin
    
    * Research use only
- Applications
  - Application
    
    Flow Cytometry; Functional Assays; Immunocytochemistry; Immunohistochemistry; Immunoprecipitation