CyFlow™ CD62L FITC

CyFlow™ CD62L FITC

Catalog Number:
A001343866SYS
Mfr. No.:
AX041427
Price:
$456
  • Size:
    0.1 mg (0.2 mL)
    Quantity:
    Add to Cart:
      • Overview
        • Please contact us at for specific academic pricing.

          Background

          CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).

      • Properties
        • Host
          rat
          Antibody Type
          monoclonal
          Isotype
          IgG2a
          Reactivity
          mouse
          Clone
          MEL-14
          Immunogen
          C3H/eb mouse B cell lymphoma 38C-13
          Conjugate
          FITC
          Formulation
          The reagent is provided in phosphate buffered saline (PBS) solution, pH ≈7.4, containing 0.09% (w/v) sodium azide.
          Storage
          Avoid prolonged exposure to light. Store in the dark at 2-8°C. Do not freeze.
          Concentration
          0.5 mg/mL
          Regulatory Status
          RUO
          Antigen
          L-selectin

          * Research use only

      • Applications
        • Application
          Flow Cytometry
          Application Description
          The reagent is designed for Flow Cytometry analysis. Suggested working usage is 6·µg/ml. Indicated dilution is recommended starting point for use of this product, but working concentrations should be validated by the investigator.

          Emission Maximum: 518 nm
          Excitation Maximum: 490 to 495 nm

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