Cy5 Boc-hydrazide (non-sulfonated)

- Overview
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    Background
    
    Boc-protected Cy5 hydrazide is a reactive dye for the labeling of aldehydes and ketones with high aqueous solubility. Trifluoroacetic acid or other strong acid can remove the Boc-(tert-butoxycarbonyl) protective group. Reactive hydrazide can couple with various carbonyl groups yielding Cy5-labeled molecules. For biomolecule labeling, the labeling reagent has low aqueous solubility, using of organic co-solvent to dissolve this molecular is necessary for efficient reaction. First, Cyanine dye should be dissolved in organic solvent and then added to a solution of biomolecule in appropriate aqueous buffer.
- Properties
  - Categories
    
    carbonyl-reactive dye
    
    Alternative Name
    
    1-(6-(2-(tert-butoxycarbonyl)hydrazinyl)-6-oxohexyl)-3,3-dimethyl-2-((1E,3E,5E)-5-(1,3,3-trimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3H-indol-1-ium
    
    Molecular Formula
    
    C37H49ClN4O3
    
    Molecular Weight
    
    633.26
    
    Purity
    
    98.00%
    
    Solubility
    
    good in dichloromethane, polar organic solvents (DMF, DMSO), alcohols, low in water
    
    Storage
    
    24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.
    
    SMILES
    
    CC(C1=CC=CC=C1N/2C)(C)C2=C/C=C/C=C/C3=[N+](CCCCCC(NNC(OC(C)(C)C)=O)=O)C4=CC=CC=C4C3(C)C
    
    * For Research Use Only