Cy3 hydrazide (non-sulfonated)

- Overview
  - Please contact us at for specific academic pricing.
    
    Background
    
    Cy3 hydrazide is a carbonyl-reactive dye, an analog of Cy3® hydrazide. Cyanine3 dyes have been used to label biological molecules for fluorescence imaging and other fluorescence-based biochemical analysis. They are widely used for labeling peptides, proteins and oligos etc.Cy3 hydrazide can be used to label various carbonyl-containing molecules such as antibodies and other glycoproteins after periodate oxidation, proteins which have undergone deamination or oxidative stress, or reducing saccarides. Cyanine3 is compatible with a number of fluorescent instruments.
    
    Pan D, Qin H, Cooperman BS. Synthesis and functional activity of tRNAs labeled with fluorescent hydrazides in the D-loop. RNA. 2009 Feb;15(2):346-54.
    Tamarit J, de Hoogh A, Obis E, et al. Analysis of oxidative stress-induced protein carbonylation using fluorescent hydrazides. J Proteomics. 2012 Jun 27;75(12):3778-88.
    Kameyama A, Kaneda Y, Yamanaka H, et al. Detection of oligosaccharides labeled with cyanine dyes using matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem. 2004 Aug 1;76(15):4537-42.
- Properties
  - Categories
    
    carbonyl-reactive dye
    
    Alternative Name
    
    1-(6-hydrazinyl-6-oxohexyl)-3,3-dimethyl-2-((1E,3E)-3-(1,3,3-trimethylindolin-2-ylidene)prop-1-en-1-yl)-3H-indol-1-ium chloride hydrochloride
    
    Molecular Formula
    
    C30H40Cl2N4O
    
    Molecular Weight
    
    543.57
    
    Appearance
    
    A solid
    
    Purity
    
    96.13%
    
    Solubility
    
    ≥54.4 mg/mL in DMSO; ≥48.2 mg/mL in EtOH; ≥50.8 mg/mL in H2O
    
    Storage
    
    Store at -20°C
    
    SMILES
    
    CN1C2=CC=CC=C2C(C)(C)/C1=C\C=C\C3=[N+](CCCCCC(NN)=O)C4=CC=CC=C4C3(C)C.[Cl-].Cl
    
    * For Research Use Only