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CUDC-101

CUDC-101

Catalog Number:
I001528157REA
Mfr. No.:
EI-HDC-010
Price:
$414
  • Size:
    5 mg
    Quantity:
    Add to Cart:
    Add to Cart
      • Overview

        • 7-((4-((3-ethynylphenyl)amino)-7-methoxyquinazolin-6-yl)oxy)-N-hydroxyheptanamide

          CUDC-101 is a novel hybrid dual-acting HDAC and receptor tyrosine kinase inhibitor. It is a potent HDAC inhibitor which also inhibits EGFR and HER2,IC50 = 4.4, 2.4 and 15.7 nM respectively. It not only blocks EGFR and HER2 but also attenuates multiple compensatory pathways such as AKT, HER3 and MET which enable tumor cells to escape the effects of conventional EGFR/HER2 inhibitors.

          Please contact us at for specific academic pricing.

      • Properties
        • Appearance
          White to off-white powder
          Solubility
          Solubilization: May be dissolved in DMSO (25 mg/ml)
          Storage
          Store desiccated as supplied at -20°C for up to 2 years. Store solutions at-20°C for up to 1 month.

          * For Research Use Only.

      • Applications
        • Application
          Epigenetic Inhibitors

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